| dc.description.abstract | Staphylococcus aureus, one of the five most common causes of infections
after injury or surgery, has emerged in recent years as an important public
health concern because of the appearance of multi-drug resistant strains. Multidrug resistant (MDR) strains of staphylococci have been reported with increasing
frequency worldwide, including isolates that are resistant to methicillin,
lincosamides, macrolides, aminoglycosides, fluoroquinolones, or combinations of
these antibiotics. This study determined the pattern of resistance of S. aureus
isolated from healthy people in Southern Viet Nam to ten commonly used
antibiotics including Ampicillin, Cephalexin, Meropenem, Kanamycin,
Erythromycin, Clindamycin, Tetracycline, Vancomycin, Ciprofloxacin and
Linezolid by using disc diffusion technique. The isolates were highly resistant
to Ampicillin (95.83%), but had low and very low resistance to Tetracycline
(16.67%), Ciprofloxacin (16.67%), Linezolid (8.33%) and Vancomycin (4.17%).
Our results also recorded the prevalence of MDR S. aureus in Vietnamese
community with percentage of 54.17% while only 4.17% of all studied strains
were susceptible to all tested antibiotics. This result indicated the severe
situation of drug abuse in Vietnamese community and the need for better
enlightenment campaign against the use of drug without instruction. In
conclusion, our data provided essential information on the distribution of MDR S.
aureus in community which would aid clinicians in prescribing antibiotics for
treatment of community- acquired S. aureus infections, predicting emergent
outbreaks of resistant S. aureus strains and even helping in setting up public
health policy.
Key words: Staphylococcus aureus, multi-drug resistance, antibiotics, healthy
people | en_US |
