Study on tissue reactions against liquid silicone injected into human body

Abstract

Subcutaneous injection of liquid silicone for cosmetic purposes is a fairly common approach in Asian countries and Vietnam. Liquid silicone has not been completely inert substance and caused serious consequences in terms of allergic diseases of strange objectives as well as aesthetic for those who have been injected this kind of alloplastic. The epidemy of tissue reactions and disorders evoked by liquid silicone injected to various anatomical sites is still a question to continue to investigate. Study on 100 patients that were admitted to Le Hanh Clinic and Cho Ray Hospital to be operated with removal of liquid silicone injected into nasal tissue for cosmetic purpose has arose the histology of lesions, clinical feature manifestation of patients and types of biological reactions in human body. Those objects were carried out based mainly on the anatomopathologic process, which were comprised three critical staining methods for analyzing anatomopathologic pattern of diseased tissue. Those classifications and evaluations of body reactions against liquid silicone injected subcutaneously are the essential base for finding the effective method for removal of siliconoma and reconstruction of the nasal pyramid. Beside that, this study also raises the strictly recommendation of concerning silicone using and treatment as well as contribution to prevention campaign against illegal injection of liquid silicone.