| dc.contributor.author | Quyen, Vu Thi Le | |
| dc.date.accessioned | 2014-01-14T07:49:04Z | |
| dc.date.accessioned | 2018-05-30T06:18:49Z | |
| dc.date.available | 2014-01-14T07:49:04Z | |
| dc.date.available | 2018-05-30T06:18:49Z | |
| dc.date.issued | 2013 | |
| dc.identifier.uri | http://10.8.20.7:8080/xmlui/handle/123456789/882 | |
| dc.description.abstract | This study investigates antioxidant and antidiabetic activity of ethyl acetate extract
of Euphorbia Thymifolia Linn and two flavonoids, Luteonin (EL01) and quercetin-3-O- arabinofuranoside (EL02), were purified and identified from ethyl acetate extract. The antioxidant potential was evaluated by 2, 2-diphenyl-1-picrylhydrazyl (DPPH)
radical scavenging assay. The antidiabetic activity was analyzed by inhibiting the α- glucosidase activity. Total phenolic and flavonoid content was also determined. The EL02 showed a strong ingredient of antioxidants with IC50 of 0.013±0.50 µg/mL that is higher than Ascorbic acid with IC50 of 0.097±0.29 µg/mL. The EL02 also had a potential in antidiabetic activity with IC50 of 11.76±0.18 µg/mL, whereas IC50 of positive control, Acarbose, was 250.4±0.014 µg/mL.
Key words: Euphorbia Thymifolia Linn, antioxidant activity, antidiabetic activity, Luteonin, Quercetin-3-O-arabinofuranoside | en_US |
| dc.description.sponsorship | Dr Hoang Le Son | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | International University HCMC, Vietnam | en_US |
| dc.relation.ispartofseries | ;022001045 | |
| dc.subject | Pharmacology -- Drugs -- Materia medica | en_US |
| dc.title | Evaluation of pharmacological activity of flavonoids in Euphorbia Thymifolia Linn | en_US |
| dc.type | Thesis | en_US |
