| dc.description.abstract | The aim of the presented study was to determine the antibacterial and antioxidant activity of Perilla frutescens essential oils and extraction method in relation to yield essential oil extraction. The essential oil was extracted by microwave-assisted extraction and hydrodistillation methods, which was the same extraction condition, the microwave-assisted extraction method gives the higher product yields than hydrodistillation method. The dominant compounds of essential oil, determined by GC-MS, were: Perillal(53.798%), D-Limonene(14.174%), Caryophyllene( 10.155%) and (Z,E)--Farnesene( 9.683%). Perilla essential oil showed bacterial activity against 2 Gram-negative and 2 Gram-positive test bacteria with minimum inhibition concentration (MIC) values ranging from 28.13 to 112.50 μg/ml. The essential oil was subjected to screening for the possible antioxidant activity by using the 2.2-diphenyl-1-picrylhydrazyl(DPPH) assay. The free radical scavenging capacity of the essential oil was determined by an IC50 value of 18.78mg/ml.
Keywords: Perilla frutescens, essential oil, microwave-assisted extraction, hydrodistillation, GC-MS, antibacterial activity, antioxidant activity, DPPH. | en_US |
