| dc.description.abstract | In today's rapidly developing world, people are becoming increasingly busy with their
lives, leading to various health issues. Abnormal blood pressure levels, such as hypertension
or hypotension, are among the primary causes of diseases such as cardiovascular disorders,
stroke, and compromised kidney function. Therefore, it is crucial to enhance knowledge and
develop methods for effectively controlling blood pressure. Recognizing the similarity of
blood pressure indices between mice and humans, and considering medication as the gold
standard for hypertension treatment, mouse models are commonly employed in laboratory
settings to test blood pressure medications. Thus, designing and constructing a blood pressure
measurement device specifically tailored for mice in laboratory environments becomes
essential for improving the efficiency of such experiments. The developed blood pressure
measurement device for mice covers a range of 0mmHg to 200mmHg and combines two
methods: Photoplethysmography (PPG) and the Method of Volume pressure recording. This
integration enables the measurement of blood pressure from a specific part of the mouse.
Two sensors are utilized to capture pressure signals in the air system and PPG signals from
the mouse's tail, respectively. Five mice were trained and employed in this experiment,
yielding estimations of blood pressure indices. In conclusion, the development of a blood
pressure measurement device specifically designed for mice in laboratory settings addresses
the growing need for effective experimentation. This device, employing PPG and the Method
of Volume pressure recording, provides an opportunity to estimate blood pressure in mice
accurately. However, further optimization is necessary to enhance the device's usability and
efficiency. | en_US |
