| dc.description.abstract | Healing a wound is one of the most complex processes in the body, requiring
several synchronized cellular actions. Death can result from chronic wounds.
Traditional wound dressings are applied directly to wounds to promote healing, but
there are some drawbacks. Because these dressings do not provide enough wound data,
doctors might miss the optimal time to alter treatment. This thesis presents the design
and implementation of a comprehensive biosensor platform and measurement
equipment for monitoring the process of wound healing. Two methodologies is
suggested for the creation of a measurement apparatus: one utilizing an RGB Color
Sensor with an Infrared filter, and the other employing an OV2640 camera. Both
systems measure RGB values within the detecting zone of the biosensor patch for a
thorough diagnostic of wound healing. However, the second approach has
demonstrated superior performance compared to the first. The device is equipped with
an MLX90614 sensor, which includes an infrared thermometer. The MLX90614 and
the commercial variant CK-T1803 have demonstrated equal performance
characteristics. The device is a biosensor platform that is capable of measuring pH,
moisture, and uric acid content on the skin. A biosensor patch, which is a type of
microfluidic paper-based analytical device, is constructed. The melted wax soaks into
the filter paper, forming distinct hydrophobic barriers. The pH sensor, which employs
phenol red, exhibits chromatic transitions from yellow to purple in reaction to pH
fluctuations ranging from 6.5 to 8.5. The moisture sensor utilizes cobalt chloride
enclosed in polyvinyl alcohol, exhibiting reversible color changes (from blue to light
blue to pink) in response to humidity levels. The sensor's range of measurement spans
from 45% to 90% humidity, and its ability to be used again is due to its reversibility.
Due to the limitations imposed by the author, the successful detection of uric acid using
colorimetric response has not been obtained. To increase the diagnosis of wound
conditions, it is recommended to expand the project by further research, additional
improvements, optimization. If both devices were improved, the electrical device and
the biosensor device would have significant promise for monitoring wound healing | en_US |
