| dc.description.abstract | Hydraulic conductance model serves as a comprehensive and reliable framework
for assessing dentin permeability, a critical factor in understanding and addressing dentin
hypersensitivity. By employing this model, the investigation thoroughly examines and
compares the effectiveness of various compositions aimed at comparing dentin
permeability. The efficacy of remineralizing agents in reducing dentin permeability
through tubule occlusion using a fluid filtration device operating at 150 cmH2O (14.7 kPa)
pressure should be assessed. Nine bovine dentin discs of 300 ± 50 m width was prepared
and randomly divided into 3 groups (n = 3). Group 1: HA, Group 2: 20TCP-80HA, Group
3: 80TCP-20HA which was synthesized by water-based method. Dentin permeability was
measured after treatment and saline immersion for 1, 3, 5, 7 days. Data were analyzed by
one-way ANOVA. Each treatment agent notably decreased dentin permeability right after
its application. All tested agents decrease permeability after 1 day of saline immersion.
Notably highlighting the superior performance of 80TCP-20HA in reducing dentin
permeability significantly when compared to 20TCP-80HA after 1 day. No significant
difference was found in the following days. This finding underscores the potential of
80TCP-20HA as a promising candidate for dentin hypersensitivity treatment due to fast
remineralizer and dentin occlusion effect. The study contributes valuable insights into the
development of in vivo studies for managing dentin hypersensitivity, emphasizing the
significance of composition optimization in enhancing treatment outcomes. | en_US |
