| dc.description.abstract | Clinacanthus nutans (Burm.f.) Lindau belongs to the family of Acanthaceae
including many species, which are known to have medical properties. There were
many researchers had tested its leaves biological activities. This research aims to
investigate antioxidant and anticancer activity of its body. β-Sitosterol-3-O- β
glucopyranoside, β-Sitosterol-3-O- β glucoside and sub- fraction F-III were
extracted and identified from ethyl acetate extract. Their structure were
determined by compared with other published data. DPPH Scavenging Assay was
used to evaluate the antioxidant activity. The anticancer activity was evaluated
on HepG2, NCI H460, MCF-7 and Hela. The sub-fraction F-III showed quite
strong cytotoxicity when against HepG2 with IC50 value of 36.80 µg/ml but no
effect on antioxidant assay.
Key words: Clinacanthus nutans, β-Sitosterol-3-O- β glucoside, β-Sitosterol-3-O-
β glucopyranoside, HepG2, DPPH, RSB. | en_US |
