| dc.description.abstract | Preimplantation development is a process in which an embryo develops from zygote
to blastocyst. Normally, good quality embryos divide into two-cell at 24 h, four-cell
at 36 h, eight-cell at 48 h, morula at 72 h and blastocyst at 96 h. However, some
embryos delay their division. Therefore, the question raised here is that does this
delay lead to some consequences? Despite many researches about first cell division,
there are little studies on the effects of timing of it on the future development and
the quality of the embryos. In this study, effects of the timing of the first
differentiation of fertilized mouse zygote on the developmental ability and embryo
quality during preimplantation development was examined. Embryos was divided
into 2 groups to study about preimplantation and stained at expanded blastocysts to
determine the quality of the embryos. The results showed that early cell division
can improve the percentage of embryos developing to blastocysts and also the
number of ICM in embryos. On the other hand, late cell division reduce the number
of embryos developing to full-term and the embryo quality.
Key words: In vitro fertilization, mouse embryos, in vitro culture, preimplantation
development, timing of the first cell division, embryo quality | en_US |
