| dc.description.abstract | In order to survive in a highly competitive environment, Streptomyces genus of
Streptomycetaceae family must produce secondary metabolites known as
antimicrobial agents, notably antibiotics to inhibit or kill other microorganism to
seize nutrition, space and oxygen. Nowadays, more than 70% of total natural origins
antibiotics still deprived from Streptomyces which make them one of the most
prolific antibiotics producers in pharmaceutical industry. In this project, soil
samples were taken from specific sites with high probability of pathogenic bacteria
occurrence in Ho Chi Minh City to isolate Streptomyces species and evaluate their
potential of producing antimicrobial compounds. In total, we have obtained 54
isolates from 3 different locations. Among those, two isolates (LTB08 and LTB50)
have particularly high antimicrobial activity against Staphylococcus aureus
ATCC29123 and moderate antimicrobial activity against Pseudomonas aeruginosa
ATCC9027. It showed that sewage infested soil can be a potential environmental
niche to isolate Streptomyces species with promising antimicrobial property. | en_US |
