| dc.description.abstract | Trichophyton rubrum is the most common dermatophyte in the world with the highest
prevalence such as in Korea. The infections which caused by this world-wide distributed
dermatophyte can be kindly persistent and therefore it difficult to treat, the partly
reason is the decreased efficiency of the host’s immune response. The present treatment
strategies mostly affect the metabolic active fungus with no effect to the spores.
The aim of this study was to test the antifungal activity of lemon seed extract on
Trichophyton rubrum growth. The mixture of lemon seed extract with different ratios
and concentration, certain amount of inoculum and medium in order to determine the
Minimum Inhibitory Concentration (MIC) which against T.rubrum. The antifungal of
lemon seed extract is belonging to the amount of limonene via broth microdilution and
agar plate test and it was characterized as a fungicidal effect. The gained results of this
study have indicated that the extract of lemon seed showed not only the statistically
significant reduction of T.rubrum colony formation at 8% in agar test and 9% at broth
test with the ratio of 1:4 v/v but also the improved herbal advantages of aqueous
extracts of lemon seed usage against the growth and development of T.rubrum. In
summary, the lemon seed extract could effectively inhibit the growth of T.rubrum at the
selectively applied concentration. | en_US |
