Caulerpa Lentillfera Extract Loaded Cream Formulation And Its Antioxidant Activity

Abstract

In this study creams were formulated dependent on the anti-oxidant capability of extracts and its analysis. Antioxidant activity of ethanolic extract of Caulerpa lentillifera was assessed by using stable 2,2 -Diphenyl-1-picryl hydrazyl (DPPH). Caulerpa lentillifera is commonly ingredient used in food, cosmetics, medicine. It contains flavonoid which roles as antioxidant. The cream was formulated into four formulas; extract concentrate 0% (F0), 0.5% (F1), 1.5% (F2) and 2.5% (F3). The creams were formulated with olive oil, vitamin E acetate, zinc oxide with same concentrations namely F1 to F4. During stability studies, the creams were to be relatively stable accordingly ICH guidelines 40±2ᵒC / 75±5% RH for 1 months. The formula is analyzed on different parameters like pH, organoleptic properties, homogeneity, after feel, emulsion type, stability studies at 40 °C, physical stability of cream and viscosity test. If can be concluded that this creams contain antioxidant property as provision of a barrier can be used to protect the skin and avoid wrinkles due to aging of the skin.