| dc.description.abstract | In this study, subcritical (CO2 + Ethanol) fluid extraction of Curcuma aromatica
(C. aromatica) rhizomes was carried out at 45 oC, 300 bar to study the
influence of different concentrations of ethanol used as a co-solvent (5-25%
v/v) on the total yield, total phenolic content, total flavonoid content and
antioxidants capacity of the oleoresins. The highest extraction yield was
achieved by using 25% v/v ethanol co-solvent while extraction with 15% v/v
ethanol gave the greatest total phenolic content (66.31 ± 0.70 mg GAE/g
sample), total flavonoid content (61.99 ± 0.54 mg QE/ g sample) and IC50
value for DPPH (0.735 ± 0.36 mg/mL). Additionally, the extraction efficiency
of subcritical fluid extraction was compared to that of supercritical fluid
extraction (SFE), Soxhlet extraction (S.E) and pressurized solvent extraction
(PSE). Although subcritical fluid extraction did not give a maximum yield
among four methods, it however provides the advantage of exhibiting the
potential biological activities at reduced extraction time and less solvent
consumption. Therefore, this method could be a promising alternative for
extraction of oleoresins from C. aromatica. | en_US |
