| dc.description.abstract | Lindera myrrha MEER is an important and commonly used plant for its
medicinal and pharmacological properties. This study was conducted to
investigate the antioxidant and anti-HepG2 cell line activity of Lindera myrrha
MEER roots. For antioxidant activity, DPPH assay was done. The results showed
that the half-maximal inhibitory concentration (IC50) of methanol extract, hexane
fraction extract, chloroform fraction extract, ethyl acetate fraction extract,
aqueous fraction extract were 0.07 ± 4.49, 0.24 ± 3.36, 0.11 ± 2.79, 0.07 ±
4.09 and 0.16 ± 5.12 mg/mL, respectively. In all of fraction extracts, the ethyl
acetate fraction extract exhibited the highest antioxidant activity. For anti-HepG2
cell line activity with MTT assay, at the concentration of 800 µg/mL, hexane
fraction extract and chloroform fraction extract inhibited 77.92 ± 2.57%, 62.21
± 1.04%, respectively. Besides, the methanol extract, ethyl acetate fraction
extract and aqueous fraction extract of Lindera myrrha MEER roots did not show
any significantly affect viability nor were it toxic to hepG2 cells at effective
concentrations. | en_US |
