| dc.description.abstract | Silk sericin has made highlighted in scientific research due to its great
biochemical properties, its compatibility with other materials and
applications in many industries. Bombyx mori is one of the great sources
to extract high yielded sericin. Because of evaluating sericin with two
different treatments, this project was established. The autoclave was the
chosen method to separate silk sericin from cocoons. There were two
samples: sample A was originally extracted sericin, and sample B- a half
of yielded sericin extract was then sonicated by the ultrasonic processor.
The yielded records by autoclaving were 16.8±1.74% and 2.43±0.13%
(sample A and sample B, respectively). Most of the protein found in the
sample A was much bigger and had a higher tendency of aggregation as
well as flocculation than in sample B (4158.4±900.7 nm and 210.4±71.1
nm, respectively). Though they shared similar patterns of Fourier
Transform Infrared (FTIR), they differed from some biochemical intensity.
The results showed that sonicated sample B absorbed moisture better
than sample A, resulting in the promising ingredient in a moisturizing
skincare products. Additionally, sample B dominated sample A at the
antioxidant property, whose IC50 was at 2017 μg/mL when compared to
2215 μg/mL for sample A. Especially, two samples were able to reduce
both Escherichia coli and Staphylococcus aureus growth for only 6 hours
at concentrations above 6.25 mg/mL. To summarize, sample B is a
potential ingredient employed in beauty products; however; it must be
researched further and modified with other materials so as to boost its
biochemical properties. | en_US |
