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dc.contributor.advisorNguyen, Thi Lan Phi
dc.contributor.authorNguyen, Hoang Ngoc Tu
dc.date.accessioned2024-09-17T07:40:51Z
dc.date.available2024-09-17T07:40:51Z
dc.date.issued2022-09
dc.identifier.urihttp://keep.hcmiu.edu.vn:8080/handle/123456789/5692
dc.description.abstractCashew nut testa (CSNT), the coat/cover of the cashew nut, is often discarded because of its bitter, astringent taste though it concludes a quantity amount of antioxidant compounds. Due to the above fact, the cashew nut testa extract (CSNTE) would have lots of valuable hydrolyzable tannins that are vital to applied in the food technology and essential to research. In this study, to fabricate the use of CSNT, its extract loaded to the nanoparticles by using double nanoemulsion method. Other components were Tween80 – hydrophilic emulsifier, coconut oil – oil phase, double distilled water (DDW) – aqueous phase. In two separated nanoemulsion system carried different emulsifiers, respectively, Lecithin and Polyglycerol polyricinoleate (PGPR), and the ratios of CSNTE and carriers was adjusted 5 – 10%. The physical properties (Z-Average, PDI, Zeta-potential) of the CSNTE-loaded NPs, especially the Zeta-potential, were the indicator of stable emulsion system to encapsulate bioactive compounds. Besides, its encapsulation efficiency on functional activities, significantly delivered the percent of encapsulation capacity of the NPs. The functional activities comprised of total phenolic content (TPC), total flavonoid content (TFC), total catechin content (TCC). The optimum ratios of CSNTE and carriers for both nanoemulsion system with Lecithin and PGPR is 15:5. The primary nanoemulsion layer (W1/O) of the optimal CSNTE loaded NPs comprised of 15 wt% of CSNTE, 5 wt% of DDW in the internal water phase (20 wt %); 5 wt% of hydrophobic emulsifier (Lecithin – experiment 01, PGPR – experiment 02), 75 wt% of sesame oil in the oil phase (80 wt %). The final CSNTE loaded NPs by double nanoemulsion method (W1/O/W2) operated by 20 wt% of the primary layer, 5 wt% hydrophilic emulsifier (Tween80) and 75 wt% of DDW. The EE results of L15:5 was 69.542 ± 0.807 % of TCC, 73.774 ± 0.846 % of TFC, and 79.239 ± 0.757 % of TPC. The EE results of P15:5 was 78.110 ± 0.983 % of TCC, 79.470 ± 0.613 % of TFC, and 83.176 ± 0.575 % of TCC. This study provides the optimal ratios of CSNTE and carriers in formulating of stable NPs, and the effects of lipophilic emulsifiers, Lecithin and Polyglycerol polyricinoleate (PGPR) on the physical properties and encapsulation efficiency of NPsen_US
dc.language.isoenen_US
dc.subjectCashew nut testa extracten_US
dc.subjectdouble nanoemulsion method (W/O/W)en_US
dc.subjectnanoparticlesen_US
dc.subjectencapsulation efficiency (EE)en_US
dc.subjectfunctional activitiesen_US
dc.subjecttotal phenolic content (TPC)en_US
dc.subjecttotal flavonoid content (TFC)en_US
dc.subjecttotal catechin content (TCC)en_US
dc.subjectphysical propertiesen_US
dc.subjectZ-Averageen_US
dc.subjectZeta-potentialen_US
dc.subjectpolydispersity index (PDI)en_US
dc.titleEffects Of Lipophilic Emulsifiers With Different Ratios Of Cashew Nut Testa Extract And Carriers On The Characteristics Of Nanoparticles Loaded With Cashew Nut Testa Extracten_US
dc.typeThesisen_US


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