| dc.description.abstract | The objective of the thesis project was to hydroxyfluorinate dipterocarpol derivatives to
produce a fluorinated compound. Dipterocarpol was extracted from resin with a low yield of
14% prior to its reaction with CrO3 to create lactone at a rate of around 62.8%. The lactone
is then converted to alcohol, alkene, and fluorinated derivatives with the yield of 38.28%,
71.08%, and 30.39%, respectively. In addition, mCPBA might produce an epoxide ring from
alkene derivatives of lactone under ideal circumstances and HF was used to open the
epoxide ring. Therefore, the reaction was successful with a low yield. The synthesis of the
fluorinated derivative is an entirely novel reaction with the starting material Dipterocarpol.
Consequently, the topic must explore several circumstances, including catalysts, agents,
temperature, duration, and reaction rate. The structures of all produced compounds match
to those shown in 1H NMR and 13C NMR spectra. | en_US |
