| dc.description.abstract | Annona squamosa Linn. was a traditional medicinal plant that was utilized not only in
Vietnam but also in Asia countries. It has been demonstrated to have antioxidant
properties, to be anti-obese, and to assist in preventing diabetes. The current study
aimed to explore the fatty acids, phytochemical components, and biological activities
of Annona squamosa L. seed and fruit peel from Tay Ninh, Vietnam. A. squamosa L.
seed kernels has been extracted via three different polarity solvents (n-Hexane, ethyl
acetate, and methanol). The fatty oil yield (19%) was converted into methyl esters and
analyzed by GC-MS. Six fatty acids, constituting 100% of the fatty oil, were identified
and the main compounds oleic acid (48.5%) and linoleic acid (20.9%). Oleic acid and
linoleic acid together constitute 69.4% of the unsaturated fatty acids in the oil of A.
squamosa seed extract. Seven different fractions were collected by medium performance liquid chromatography of the residue fruit peel extract. Moreover, β Sitosterol-D-glucoside was isolated successfully from the residue peel extract. The
samples were evaluated for antioxidant activity by DPPH free radical method, lipase,
and ɑ-amylase inhibition activities. Among these samples, the crude extract showed
the highest antioxidant results (24.244 ± 0.268). Meanwhile, the residue extract
showed the highest inhibition of pancreas lipase and ɑ-amylase enzymes at 19.538 ±
0.922 and 6.695 ± 0.331, respectively. In summary, Annona squamosa L. seed and
peel waste materials have low potency for drug development and can be studied further
for pharmacological aspects. | en_US |
