| dc.description.abstract | The demand for highly precise and uniform coatings on microneedles (MNs) is growing
rapidly due to their increased use in various biomedical applications, including drug
delivery, transdermal vaccination, and biosensing. This surge in demand has
necessitated the development of more advanced and efficient coating methods to meet
the requirements of these applications. However, the existing methods for coating MNs,
particularly the manual hand-dipping technique, suffer from several limitations. These
include issues related to sterility, coating uniformity, and efficiency. To address these
challenges, a novel dip coating device has been proposed and developed in this study.
The problem statement revolves around the need for a more controlled and automated
coating system that can deliver precise and uniform coatings on MNs. The manual
hand-dipping method, while widely used, presents significant challenges in terms of
sterility, uniformity, and efficiency.The proposed solution is a dip coating device that
utilizes a gas jet drying method for precision coating of MNs. This device incorporates
a stepper motor for controlled immersion, ensuring uniform coating thickness.The
methods employed in this study include an extensive literature review to identify the
limitations of existing coating methods, followed by the conceptualization and design
of the dip coating device. Prototyping and iterative testing were then conducted to refine
the device's design and performance. The results of this study indicate that the proposed
dip coating device offers significant advantages over existing methods. It provides
highly precise and uniform coatings on MNs, addressing the issues of sterility, coating
uniformity, and efficiency. The device is scalable, cost-effective, and versatile, making
it suitable for various biomedical applications. Summarize, the dip coating device
represents a significant advancement in the field of microneedle coating technology. It
has the potential to revolutionize the way MNs are coated, offering precision,
efficiency, and scalability that were previously unattainable with existing methods. | en_US |
