Naringenin Preparation From Citrus Wastes For Pharmaceutical Applications

Abstract

Naringenin, which is a flavonoid found mostly in Citrus L., plays a pivotal role in biological activities and yields potential health benefits, which contributes to pharmaceutical development. There is a rising demand for pharmaceutical products including anticancer and anti-fungal agents. Many studies were conducted on naringenin to broaden the knowledge of the compound, and clinical trials are still in progress to evaluate the final results. However, the wastes as cheap materials for increasing naringenin extractions for medicines should be exploited. This work broadly explored the detection of naringenin extracted from lemon, grapefruit, and king orange by immersion method, in which ethanol 90% was principally used to extract flavonoid content at a ratio of 1:4. Moreover, each citrus wastes were screened through UV-Vis (Ultraviolet-Visible) spectrophotometry to detect the presence of naringenin. As a result, naringenin was found mostly in citrus peels once triplication, especially lemon and grapefruit. Finally, this study contributed to further research on the optimization of naringenin through quantification check giving rise to the pharmaceutical applications in an era of development.