Surface Modifications Of Silver Particles With Chitosan, Polyethylene Glycol, Polyvinyl Alcohol, And Polyvinylpyrrolidone As Antibacterial Agents Against Staphylococcus Aureus, Pseudomonas Aeruginosa, And Salmonella Enterica

Abstract

In the field of medicine, antibiotic resistance was becoming a grave issue. At the same time, typical antibacterial agent production procedures frequently pollute the environment by using harmful chemicals. To get around these issues, a novel chemical compound, a polymer mixture (M8) composed of PVP, PVA, CS, PEG, and silver nitrate, offers remarkable promise as an ecologically friendly antibacterial agent and a potential solution to antibiotic resistance through green synthesis. After 10 hours of reaction at 80 °C, the Ag:M8 ratio achieving 100 % conversion of Ag+ to Ag0 was 0.15 g/60 mL, according to the experimental results. The nanoparticle analysis revealed a mass fraction of 39.22 ± 0.34 % and an atomic fraction of 8.1 ± 0.07 %. The particle sizes averaged 42.48 ± 10.77 nm based on FE-SEM and 44.53 nm from XRD data. In terms of antibacterial efficiency, the M8 and AgNPs composite (M8Ag) was utilized to inhibit 50 % the growth of Pseudomonas aeruginosa (PA), Staphylococcus aureus (SA), and Salmonella enterica (SAL) by a 6.25 % dilution. The data collected highlights M8Ag's potential as an effective antibacterial treatment, notably against PA.