The prevalence and pattern of HIV drug resistance mutations in antiretroviral-naïve individuals initiating antiretroviral therapy in Ha Noi, Vietnam 2012-2013.

Abstract

Our study identified a TDR of 5.4% in 130 antiretroviral-naive individuals initiating ART in Ha Noi, Vietnam 2011- 2012 using the 2009 WHO SDRM algorithm. Overall level of TDR is similar to recent studies in Vietnam. TDR to PIs was identified in 3 patients for the first time in Ha Noi. As PIs are the main component of 2nd-line therapy and the last resort for patients with drug-resistant virus in Vietnam, this study calls for further investigations into this alarming issue. KEY WORDS: Human Immunodeficiency Virus Acquired Immunodeficiency Syndrome Transmitted drug resistance Antiretroviral therapy Vietnam