dc.description.abstract | Musa balbisiana (MB) fruits are widespread as an herbal medicine with great
therapeutic potential worldwide. The present study was designed to investigate
raw materials and crude extract of MB fruits for phytochemicals by qualitative
chemical tests and standardization using purity content, chemical
characterization, total polyphenol (TPC) and flavonoid (TFC) contents to assess
the quality. Besides, antioxidant activity of crude and fractionated extracts of MB
fruits was also evaluated using in vitro models including DPPH quenching, ABTS
cation decolorization, and reducing antioxidant power assays. Results showed
that physicochemical parameters for MB fruits were within prescribed
Vietnamese Pharmacopoeia 5th edition limits. Phytochemical analysis of MB fruits
revealed the presence of flavonoids, proanthocyanidins, saponins, and
triterpenoids. The TPC was 3.92 ± 0.27 mg GAE/g d. w. and 162.64 ± 3.39 mg
GAE/g d. w. for the raw materials and crude extract respectively while the TFC
was 0.138 ± 0.002 mg QE/g d. w. and 1.222 ± 0.007 mg QE/g d. w.. Furthermore,
the crude and fractionated extracts of MB fruits has a high radical scavenging
activity. The initial sourcing and quality evaluation of crude extract can be very
effective if these preliminary studies are used as raw materials for preparations of
herbal formulations. The antioxidant potential of MB fruits can be beneficial for
nutritional and medicinal purposes. | en_US |