dc.description.abstract | Trauma wound is an inevitable health issue in life. Many researchers have
endeavored to develop multifunctional materials to enhance wound healing af ter
injury. Syzygium resinosum (Gagnep), a plant with f resh leaves and decoction, is
widely used in Vietnam and tropical countries to treat sof t tissue wounds, burns,
skin infections, and periodontal diseases. Silver nanoparticles (AgNPs) synthesized
using the herbal extract in Chitosan–Pluronic F127 copolymer (which plays roles
in enhancing healing and protecting the colloidal nanosilver and plant bioactive
components were used to create a thermosensitive polymeric nanocomposite
solution that can form a multifunctional hydrogel film on the wound surface, in
future studies. Phytochemical analysis was perf ormed to approximate the total
phenolic content using the Folin–Ciocalteu method and antioxidant activities of the
SR extract were tested using the DPPH radical scavenging assay. The synthesized
products were characterized using different techniques, such as UV−visible
spectroscopy, dynamic light scattering (DLS), X-ray diffraction (XRD), and
transmission electron microscopy (TEM). The results proved that AgNPs were
successfully synthesized in the copolymer using SR extract that would be further
studied for biomedical applications. | en_US |