| dc.description.abstract | Mushrooms belong to the fungi family and have a variety of secondary metabolites,
including various phenolic compounds and bioactive activities that act as strong
antioxidants. The purpose of the present study was to compare antioxidant activities, total
phenolics, and total flavonoid content between extracts of Agaricus bisporus (white button
mushroom) and Ganoderma lucidum (reishi mushroom), as well as to evaluate the
antioxidant activities of a facial serum containing these extracts. All mushroom samples
were extracted with 95% ethanol at room temperature for 3 days, and extracts stored at 4
degrees were determined at IC50 concentrations using the DPPH and ABTS assays. The
phenolic compound analysis was performed using the Folin-Ciocalteu reagent, and the
flavonoid content was quantified using the reaction with aluminum chloride salt.
Additionally, extracts were used to formulate facial serums, and their antioxidant abilities
were compared with those of commercially available antioxidant serums. As a result,
Ganoderma lucidum extract exhibited the strongest antioxidant capacity among the three
extracts, with IC50 concentrations by DPPH (0.309 ± 0.06 mg/ml) and ABTS (3.978 ±
0.098 mg/ml), total phenolic content (17.24 ± 0.55 mg/ml), and total flavonoid content
(31.12 ± 0.3 mg/ml). Next, the live extract of Agaricus bisporus showed IC50
concentrations by DPPH (1.267 ± 0.07 mg/ml) and ABTS (5.937 ± 0.622 mg/ml), total
phenolic content (13.65 ± 0.86 mg/ml), and total flavonoid content (9.69 ± 0.49 mg/ml).
Finally, the cooked extract of Agaricus bisporus had the lowest antioxidant activities of
the three extracts, with IC50 concentrations of DPPH (2.796 ± 0.20 mg/ml) and ABTS
(7.393 ± 0.30 mg/ml), total phenolic content (9.89 ± 0.57 mg/ml), and total flavonoid
content (9.9 ± 0.63 mg/ml). Based on the results, Ganoderma lucidum extract was the
highest antioxidant; however, the antioxidant properties exhibited by the extract of the live
Agaricus bisporus mushroom could be considered for application in cosmetics. | en_US |
